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Steven E Nissen Selected Research

Type 2 Diabetes Mellitus (MODY)

1/2024Comparison of tirzepatide and dulaglutide on major adverse cardiovascular events in participants with type 2 diabetes and atherosclerotic cardiovascular disease: SURPASS-CVOT design and baseline characteristics.
1/2022Transitioning to active-controlled trials to evaluate cardiovascular safety and efficacy of medications for type 2 diabetes.
1/2022Response to Comment On Aminian et al. Cardiovascular Outcomes in Patients With Type 2 Diabetes and Obesity: Comparison of Gastric Bypass, Sleeve Gastrectomy, and Usual Care. Diabetes Care 2021;44:2552-2563.
11/2021Cardiovascular Outcomes in Patients With Type 2 Diabetes and Obesity: Comparison of Gastric Bypass, Sleeve Gastrectomy, and Usual Care.
5/2021Association Between Achieved ω-3 Fatty Acid Levels and Major Adverse Cardiovascular Outcomes in Patients With High Cardiovascular Risk: A Secondary Analysis of the STRENGTH Trial.
10/2020Effect of C-Reactive Protein on Lipoprotein(a)-Associated Cardiovascular Risk in Optimally Treated Patients With High-Risk Vascular Disease: A Prespecified Secondary Analysis of the ACCELERATE Trial.
10/2020How Much Weight Loss is Required for Cardiovascular Benefits? Insights From a Metabolic Surgery Matched-cohort Study.
6/2020Erratum. Predicting 10-Year Risk of End-Organ Complications of Type 2 Diabetes With and Without Metabolic Surgery: A Machine Learning Approach. Diabetes Care 2020;43:852-859.
1/2020Bariatric Surgery Improves HDL Function Examined by ApoA1 Exchange Rate and Cholesterol Efflux Capacity in Patients with Obesity and Type 2 Diabetes.
1/2020Alogliptin after acute coronary syndrome in patients with type 2 diabetes: a renal function stratified analysis of the EXAMINE trial.
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Steven E Nissen Research Topics

Disease

80Coronary Artery Disease (Coronary Atherosclerosis)
02/2022 - 05/2003
75Atherosclerotic Plaque (Atheroma)
01/2024 - 02/2003
42Atherosclerosis
12/2023 - 02/2002
41Cardiovascular Diseases (Cardiovascular Disease)
05/2024 - 03/2000
41Myocardial Infarction
01/2024 - 07/2002
30Type 2 Diabetes Mellitus (MODY)
01/2024 - 11/2005
29Stroke (Strokes)
01/2024 - 11/2005
24Acute Coronary Syndrome
01/2022 - 03/2000
20Coronary Disease (Coronary Heart Disease)
01/2018 - 11/2003
17Disease Progression
02/2021 - 01/2005
16Obesity
04/2024 - 06/2006
16Heart Failure
01/2024 - 05/2003
16Inflammation (Inflammations)
12/2023 - 02/2003
15Unstable Angina
10/2022 - 07/2002
11Weight Loss (Weight Reduction)
04/2024 - 04/2008
11Atrial Fibrillation
01/2024 - 08/2015
11Hypertension (High Blood Pressure)
01/2023 - 06/2006
11Vascular Diseases (Vascular Disease)
10/2022 - 09/2007
9Body Weight (Weight, Body)
01/2024 - 04/2008
9Diabetes Mellitus
01/2021 - 06/2010
8Hypogonadism (Hypergonadotropic Hypogonadism)
02/2024 - 01/2022
8Pathologic Constriction (Stenosis)
08/2018 - 03/2003
7Rheumatoid Arthritis
09/2022 - 04/2009
6Aortic Valve Stenosis (Aortic Stenosis)
04/2024 - 05/2003
6Neoplasms (Cancer)
10/2022 - 01/2009
6Osteoarthritis
09/2022 - 04/2009
6AIDS-Related Complex (ARC)
02/2022 - 08/2014
6Metabolic Syndrome (Dysmetabolic Syndrome X)
02/2022 - 07/2006
5Thrombosis (Thrombus)
12/2023 - 08/2006
5Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy)
10/2023 - 01/2021
5Arthritis (Polyarthritis)
09/2022 - 04/2009
5COVID-19
03/2022 - 08/2020
5Dyslipidemias (Dyslipidemia)
12/2020 - 03/2007
4Chest Pain (Chest Pains)
01/2019 - 03/2000
3Cholelithiasis
01/2024 - 04/2023
3Gout
01/2024 - 04/2023
3Non-alcoholic Fatty Liver Disease
05/2023 - 01/2019
3ST Elevation Myocardial Infarction
01/2022 - 02/2003
3Hypoglycemia (Reactive Hypoglycemia)
01/2020 - 04/2008
3Ischemia
01/2019 - 03/2000

Drug/Important Bio-Agent (IBA)

62Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
01/2024 - 02/2003
36LipidsIBA
05/2024 - 11/2003
31oxidized low density lipoproteinIBA
05/2024 - 04/2006
30LDL CholesterolIBA
01/2024 - 01/2005
25HDL CholesterolIBA
03/2022 - 11/2003
24C-Reactive ProteinIBA
01/2024 - 10/2003
24Atorvastatin (Lipitor)FDA Link
01/2019 - 03/2004
21omega-Chloroacetophenone (Mace)IBA
01/2024 - 05/2010
19Rosuvastatin Calcium (Crestor)FDA Link
08/2017 - 04/2006
12Lipoproteins (Lipoprotein)IBA
05/2024 - 01/2005
12Lipoprotein(a)IBA
04/2024 - 08/2017
12evacetrapibIBA
10/2022 - 11/2011
11CholesterolIBA
01/2024 - 02/2007
10Cholesterol Ester Transfer ProteinsIBA
10/2022 - 12/2008
10Triglycerides (Triacylglycerol)IBA
03/2022 - 03/2007
9evolocumabIBA
01/2023 - 06/2016
8Testosterone (Sustanon)FDA Link
02/2024 - 01/2022
8Naproxen (Naprosyn)FDA LinkGeneric
09/2022 - 04/2009
8Celecoxib (Celebrex)FDA Link
09/2022 - 04/2009
8Ibuprofen (Motrin)FDA LinkGeneric
09/2022 - 04/2009
8CalciumIBA
01/2021 - 01/2007
8HDL LipoproteinsIBA
12/2020 - 03/2006
8Apolipoprotein A-I (Apolipoprotein A1)IBA
02/2016 - 11/2003
7Biomarkers (Surrogate Marker)IBA
12/2023 - 01/2005
7Insulin (Novolin)FDA Link
02/2022 - 04/2008
7Phenobarbital (Luminal)FDA Link
08/2018 - 03/2003
68- hydroxy- 2,2,14,14- tetramethylpentadecanedioic acidIBA
01/2024 - 04/2023
6alogliptinIBA
01/2020 - 10/2011
6Pioglitazone (Actos)FDA Link
01/2019 - 11/2005
5EnzymesIBA
11/2023 - 10/2003
5LDL Lipoproteins (beta Lipoproteins)IBA
12/2020 - 01/2005
5ApolipoproteinsIBA
01/2018 - 02/2007
5Hypoglycemic Agents (Hypoglycemics)IBA
01/2016 - 04/2008
5Amlodipine (Norvasc)FDA LinkGeneric
04/2012 - 11/2004
5EnalaprilFDA LinkGeneric
04/2012 - 11/2004
5Pravastatin (Pravachol)FDA LinkGeneric
07/2008 - 03/2004
4Glucagon-Like Peptide 1 (GLP 1)IBA
04/2024 - 01/2016
4Hemoglobins (Hemoglobin)IBA
02/2024 - 04/2008
4LiraglutideFDA Link
01/2024 - 11/2013
4CreatinineIBA
11/2023 - 03/2007
4MYK-461IBA
10/2023 - 01/2021
4Antihypertensive Agents (Antihypertensives)IBA
01/2023 - 11/2004
4Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA
09/2022 - 04/2009
4TroponinIBA
08/2021 - 03/2000
4Apolipoproteins B (ApoB)IBA
12/2020 - 07/2008
3Glucose (Dextrose)FDA LinkGeneric
04/2024 - 05/2014
3Myosins (Myosin)IBA
01/2023 - 12/2022
3Dihydrotachysterol (AT 10)IBA
03/2022 - 01/2020
3Glycated Hemoglobin (Glycosylated Hemoglobin)IBA
11/2021 - 01/2011
3Proprotein Convertase 9IBA
02/2021 - 12/2016
3Proteins (Proteins, Gene)FDA Link
01/2019 - 11/2007

Therapy/Procedure

98Therapeutics
05/2024 - 05/2003
18Bariatric Surgery
04/2024 - 04/2012
8Glycemic Control
04/2024 - 09/2007
8Gastric Bypass (Roux-en-Y Gastric Bypass)
03/2022 - 04/2012
8Gastrectomy
03/2022 - 04/2012
5Percutaneous Coronary Intervention
08/2020 - 02/2003
4Drug Therapy (Chemotherapy)
01/2024 - 12/2020
3Operative Surgical Procedures
12/2023 - 11/2021
3Secondary Prevention
01/2022 - 11/2003